Takahiro J. Nakamura

Lack of Period1 accelerates colorectal tumorigenesis in ApcMin/+ mice

This study shows that deleting Per1 in ApcMin/+ mice increases intestinal polyp formation and elevates β-catenin levels, suggesting Per1's tumor-suppressive role in colorectal tumorigenesis.

Induction of cell death in U2OS human cancer cells by Ta3N5

This study evaluates the cytotoxicity and cell death mechanisms of Ta3N5 in U2OS cells under various light conditions and doses.

Diurnal variation of brain activity in the human suprachiasmatic nucleus

This study investigates diurnal variation in human SCN activity using perfusion imaging, finding higher activity at noon and lower in the early morning, aligning with rodent patterns under light conditions.

AVP neurons act as the primary circadian pacesetter cells in vivo

This study shows AVP neurons determine the circadian period of the SCN network by controlling behavioral rhythms through period lengthening.