Author

Patrick Maschmeyer

Max Delbrück CenterORCID 0000-0002-1705-5302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Anshul Bharat KundajeiD· 2 shared Ansuman T. SatpathyiD· 2 shared Caleb A. LareauiD· 2 shared Frank A. BuquicchioiD· 2 shared Jacob C. GutierreziD· 2 shared Leif S. LudwigiD· 2 shared Lena NitschiD· 2 shared Yajie YiniD· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Anshul Bharat KundajeORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 23, 2023

Codon affinity in mitochondrial DNA shapes evolutionary and somatic fitness

Caleb A. Lareau, Yajie Yin, Jacob C. Gutierrez…·Ansuman T. Satpathy

The paper identifies a synonymous mtDNA variant that affects codon-anticodon affinity and shows its impact on cellular fitness in immune cells.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 20, 2022

Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells

Caleb A. Lareau, Sonia M. Dubois, Frank A. Buquicchio…·Leif S. Ludwig

The paper uses single-cell multi-omics to study how pathogenic mtDNA mutations are subject to purifying selection in immune cells from Pearson syndrome patients.

4 citations

𝕏 PostBluesky