Evolutionary and structural basis of SLAM utilization in morbilliviruses - Its implications for host range and cross-species transmission
Ayumu Hyodo, Fumio Seki, Kento Fukuda, Kaede Tashiro, Yuki Kitai, Yukiko Akahori, Hideko Watabe, Hiroshi Katoh, Rikuto Osaki, Daisuke Takaya, Norihito Kawashita, Hideo Fukuhara, Satoshi Ikegame, Tomoki Yoshikawa, Park Eunsil, , Makoto Takeda
This study investigates how morbilliviruses use SLAM receptors across species, finding that most can use multiple SLAMs except human SLAM, and that MV adapts to bat SLAM with a single mutation.
bioRxiv · Feb 18, 2025 · PreprintMicrobiology