Molecular BiologybioRxivPreprint
Nobiletin, a Polymethoxyflavonoid, Activates the Desuccinylase Activity of SIRT5 and Prevents the Development of Heart Failure
Yoichi Sunagawa, Masafumi Funamoto, Toshihide Hamabe‐Horiike…·Tatsuya Morimoto
This study shows nobiletin prevents heart failure by enhancing SIRT5 desuccinylase activity, which inhibits p300-HAT activity in mice.
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