BioinformaticsbioRxivPreprint
Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment
Ignaty Leshchiner, Dimitri G. Livitz, Justin F. Gainor…·Gad A. Getz
PhylogicNDT statistically reconstructs cancer driver timing, subclonal phylogenies, and population dynamics from single- or multi-timepoint sequencing, revealing subtype-specific trajectories and therapy resistance evolution across 498 lung adenocarcinomas.
79 citations