Author

Justin F. Gainor

Massachusetts General HospitalORCID 0000-0001-8697-4081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Alice Tsang ShawiD· 2 shared Chip StewartiD· 2 shared Gad A. GetziD· 2 shared Ignaty LeshchineriD· 2 shared Jaegil KimiD· 2 shared Mari A. Mino-KenudsoniD· 2 shared Aaron Timothy GriffiniD· 1 shared Aina Zurita MartineziD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenomics

Alice Tsang ShawORCID

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2 papers

Recent·Most cited

Integrative Analysis of Checkpoint Blockade Response in Advanced Non-Small Cell Lung Cancer

Arvind Ravi, Justin F. Gainor, Monica B. Arniella, Mark Holton, Samuel S. Freeman, Chip Stewart, Ignaty Leshchiner, Jaegil Kim, Yo Akiyama, Aaron Timothy Griffin, Natalie I. Vokes, Mustafa Sakhi, Vashine Kamesan, Hira A. Rizvi, Biagio Ricciuti, , Matthew David Hellmann

This study identifies molecular and immune features associated with response to anti-PD-(L)1 therapy in NSCLC using a cohort of 393 patients.

bioRxiv · Mar 21, 2022 · PreprintGenomics

Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment

Ignaty Leshchiner, Dimitri G. Livitz, Justin F. Gainor, Daniel Rosebrock, Oliver Spiro, Aina Zurita Martinez, Edmund A. Mroz, Jessica J. Lin, Chip Stewart, Jaegil Kim, Liudmila Elagina, Ivana Božić, Mari A. Mino-Kenudson, Marguerite M. Rooney, Sai‐Hong Ignatius Ou, , Gad A. Getz

PhylogicNDT statistically reconstructs cancer driver timing, subclonal phylogenies, and population dynamics from single- or multi-timepoint sequencing, revealing subtype-specific trajectories and therapy resistance evolution across 498 lung adenocarcinomas.

bioRxiv · Feb 16, 2019 · PreprintBioinformatics