Author

Alan M. Downey‐Wall

Northeastern UniversityORCID 0000-0002-1770-1706Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Katie E. LotterhosiD· 4 shared Steven RobertsiD· 4 shared Yaamini R. VenkataramaniD· 4 shared Hollie M. PutnamiD· 2 shared Justin B. RiesiD· 2 shared Samuel J. WhiteiD· 2 shared Ariana S. HuffmyeriD· 1 shared Brett M. Ford· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersGenomics

Katie E. LotterhosORCID

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4 papers

Recent·Most cited

PhysiologyCurrent ZoologyPeer-reviewedJan 1, 2024

DNA methylation correlates with transcriptional noise in response to elevated pCO2 in the eastern oyster (Crassostrea virginica)

Yaamini R. Venkataraman, Ariana S. Huffmyer, Samuel J. White…·Steven Roberts

This study examines how DNA methylation and gene expression respond to elevated pCO2 in eastern oysters, finding sex-specific effects on transcriptional noise and gene regulation.

9 citations

non-human primateDNA methylation

𝕏 PostBluesky

GenomicsMolecular Ecology ResourcesPeer-reviewedOct 28, 2021

Invertebrate methylomes provide insight into mechanisms of environmental tolerance and reveal methodological biases

Shelly A. Trigg, Yaamini R. Venkataraman, Mackenzie R. Gavery…·Hollie M. Putnam

The paper compares DNA methylation quantification methods in corals, revealing methodological biases and environmental sensitivity differences.

23 citations

non-human primateDNA methylation

𝕏 PostBluesky

Molecular BiologyFrontiers in Marine SciencePeer-reviewedNov 12, 2020

Ocean acidification induces subtle shifts in gene expression and DNA methylation in mantle tissue of the Eastern oyster (Crassostrea virginica)

Alan M. Downey‐Wall, Louise P. Cameron, Brett M. Ford…·Katie E. Lotterhos

This study examines how ocean acidification affects gene expression and DNA methylation in the mantle tissue of Eastern oysters over time, finding subtle molecular responses and limited plasticity.

53 citations

DNA methylationbulk RNA-seq

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GenomicsFrontiers in Marine SciencePeer-reviewedApr 22, 2020

General DNA methylation patterns and environmentally-induced differential methylation in the eastern oyster (Crassostrea virginica)

Yaamini R. Venkataraman, Alan M. Downey‐Wall, Justin B. Ries…·Katie E. Lotterhos

The paper examines DNA methylation patterns in eastern oyster gonad tissue under ocean acidification conditions and identifies differentially methylated loci that may influence transcriptional control and potential inheritance.

58 citations

mouseDNA methylation

𝕏 PostBluesky