Author

Mauricio Lacerda

University of BonnORCID 0000-0002-1770-3007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Charles Tapley HoytiD· 2 shared Martin Hofmann-ApitiusiD· 2 shared Özlem MusluiD· 2 shared Andrej KonotopeziD· 1 shared Bradley W. EnglishiD· 1 shared Christian EbelingiD· 1 shared Colin J. BirkenbihliD· 1 shared Daniel Domingo‐FernándéziD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Charles Tapley HoytORCID

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2 papers

Recent·Most cited

BioinformaticsIEEE Transactions on Computational Biology and BioinformaticsPeer-reviewedJun 19, 2020

GuiltyTargets: Prioritization of Novel Therapeutic Targets with Deep Network Representation Learning

Özlem Muslu, Charles Tapley Hoyt, Mauricio Lacerda…·Holger Frohlich

GuiltyTargets prioritizes therapeutic targets using deep learning on protein interaction networks, achieving high accuracy in disease-specific target ranking and showing potential for target repositioning.

28 citations

humanprotein structure

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 8, 2019

Integration of Structured Biological Data Sources using Biological Expression Language

Charles Tapley Hoyt, Daniel Domingo‐Fernándéz, Sarah Mubeen…·Martin Hofmann‐Apitius

The paper introduces Bio2BEL, a set of Python packages that convert multi-modal biological data into Biological Expression Language for integration and analysis.

11 citations

statistical modeldatabase / resource

𝕏 PostBluesky