The Topology of Mutated Driver Pathways
Raouf Dridi, Hedayat Alghassi, Ma’en Obeidat, Sridhar R. Tayur
The paper introduces a topological framework to analyze mutated driver pathways in cancer, finding AML pathways resemble a sphere and GBM pathways resemble a genus-2 surface.
bioRxiv · Nov 30, 2019 · PreprintBioinformatics