Ma’en Obeidat

This study identifies protein biomarkers in vitreous humor and plasma that predict diabetic retinopathy progression, with significant changes observed in vitreous samples of PDR patients.

This study identifies eight novel genetic signals associated with asthma-COPD overlap through a genome-wide association analysis involving multiple cohorts.

The paper identifies proteins associated with lung function and COPD risk using integrative omics and Mendelian Randomization, finding 37 proteins with causal associations.

This study uses Mendelian randomisation to show that higher serum CC-16 levels protect against COPD risk and progression, with genetic variants linked to CC-16 expression in lung tissue.

The paper identifies SNPs with sex-specific effects on lung function traits using UK Biobank data, finding a significant interaction at rs7697189 near HHIP.

The paper identifies genetic links between impaired pulmonary function and increased lung cancer risk, showing causal relationships through Mendelian randomization and highlighting immune-related pathways.

The paper introduces a topological framework to analyze mutated driver pathways in cancer, finding AML pathways resemble a sphere and GBM pathways resemble a genus-2 surface.

The paper identifies sex-specific transcriptomic responses to smoking in human airway epithelium, revealing sexually dimorphic gene modules associated with autophagy and immune response pathways.

This study identifies three new genetic loci associated with idiopathic pulmonary fibrosis and confirms 11 previously reported ones, highlighting mTOR signaling and mitotic spindle-assembly genes in disease susceptibility.

This study expands the genetic landscape of COPD by identifying 82 risk loci, revealing associations with lung function, cell types, and comorbidities.

The paper identifies 279 new genetic signals for lung function across multiple ancestries, showing associations with COPD and pleiotropic effects.

This study identifies over 50 new genetic loci associated with pulmonary function through a multiethnic meta-analysis of 90,715 individuals.

The paper identifies 12 novel COPD loci and candidate causal genes using GWAS and lung eQTL data from 129 risk loci.