Author

Brennan Overhoff

University at Buffalo, State University of New YorkORCID 0000-0002-1779-2783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

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Ram SamudralaiD· 1 shared William MangioneiD· 1 shared Zackary FallsiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Ram SamudralaORCID

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1 paper

Recent·Most cited

BioinformaticsPharmaceuticalsPeer-reviewedDec 7, 2021

A Deep Learning Proteomic Scale Approach for Drug Design

Brennan Overhoff, Zackary Falls, William Mangione, Ram Samudrala

This paper introduces a deep learning approach to design drug-like compounds by generating molecules that mimic interaction signatures of existing drugs, showing significant behavioral similarity in 16/20 cases.

17 citations

humanproteomics

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