Membrane-targeting antimicrobials trigger lysis in Bacillus subtilis by disturbing the MreB-dependent regulation of peptidoglycan hydrolases
Kenneth H. Seistrup, Alan Koh, Henrik Strahl
This study shows membrane-targeting antimicrobials cause Bacillus subtilis lysis by disrupting MreB-dependent regulation of peptidoglycan hydrolases, not directly through membrane permeabilisation.
bioRxiv · May 4, 2026 · PreprintMicrobiology