The molecular basis of coordinated antigen switching enabling chronic infection by human malaria parasites
Joseph E. Visone, Francesca Florini, Evi Hadjimichael, Valay Patel, Kirk Deitsch
This study identifies the molecular mechanism by which var2csa functions as a switching hub to coordinate var gene expression in Plasmodium falciparum, enabling antigenic variation and chronic infection.
bioRxiv · Jul 16, 2025 · PreprintMicrobiology