Author

Brett G.M. Hughes

The University of QueenslandORCID 0000-0002-1811-0537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Ananthi Kumar· 1 shared Denise RommeliD· 1 shared Dilan PathiranaiD· 1 shared Dillon CorvinoiD· 1 shared Franziska SchneppenheimiD· 1 shared Jason MadoreiD· 1 shared Kevin ThurleyiD· 1 shared Lambross T. Koufariotis· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Ananthi Kumar

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1 paper

Recent·Most cited

ImmunologyEuropean Journal of ImmunologyPeer-reviewedNov 12, 2024

Type I interferon drives a cellular state inert to TCR-stimulation and could impede effective T-cell differentiation in cancer

Dillon Corvino, Martin Druce Batstone, Brett G.M. Hughes…·Tobias Bald

The paper identifies a subset of CD8+ TILs in HPV-HNSCC enriched for interferon-stimulated genes that are transcriptionally inert to TCR stimulation and may hinder T-cell differentiation.

DOI 10.1002/eji.202451371

humanscRNA-seq

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