Author

Bonnie L Blazer-Yost

Indiana University IndianapolisORCID 0000-0002-1899-4555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Gowthami MahendraniD· 2 shared Abigail D. Cox· 1 shared Alexandra L Hochstetler· 1 shared David AuduiD· 1 shared David Audu· 1 shared David J. Behm· 1 shared Fatemeh O. Bidgoli· 1 shared Gregory T. Knipp· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Gowthami MahendranORCID

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3 papers

Recent·Most cited

Use of Integrative Proteomic Analysis to Uncover Shared Molecular Signatures Across Distinct Forms of Hydrocephalus

Gowthami Mahendran, Piriyankan Kirupaharan, David Audu, Bonnie L Blazer-Yost

This study identifies shared and etiology-specific proteomic signatures across hydrocephalus subtypes using cross-study proteomic analysis of CSF.

bioRxiv · Nov 5, 2026 · PreprintNeuroscience

TRPV4 antagonist efficacy in a post-hemorrhagic hydrocephalus pig model

R. Timothy Bentley, Scott C. Mitchell, Robyn R. McCain, Gregory T. Knipp, David Audu, Fatemeh O. Bidgoli, Alexandra L Hochstetler, David J. Behm, Abigail D. Cox, Bonnie L Blazer-Yost

This study tests TRPV4 antagonism in a pig model of post-hemorrhagic hydrocephalus, showing it prevents ventriculomegaly and reduces intracranial pressure.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

Phosphoproteomic Insights into TRPV4 - AMPK Signaling Axis in the Choroid Plexus Epithelium: Implications for Therapeutic Targeting in Hydrocephalus

Gowthami Mahendran, Maryam Torabi, Bonnie L. Blazer‐Yost

The paper investigates the TRPV4-AMPK signaling axis in choroid plexus epithelial cells using phosphoproteomics, showing that AMPK inhibition enhances barrier tightness and suggests metformin as a potential therapeutic agent for hydrocephalus.

bioRxiv · Jul 18, 2026 · PreprintNeuroscience