GenomicsPLoS neglected tropical diseasesPeer-reviewed
Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity
Stephen R. Doyle, Catherine Bourguinat, Hugues Clotaire Nana-Djeunga…·Warwick N. Grant
This study uses genome-wide analysis to show that genetic drift and soft selective sweeps, rather than strong selection, drive loss of ivermectin sensitivity in Onchocerca volvulus.
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