Diego Ottaviani

This study uses human stem cell models to investigate IFT140 variants causing retinal dystrophy and identifies eupatilin as a potential therapeutic for cilia defects.

This paper investigates the effects of eupatilin on cilia defects in CEP290-related retinal disease models and finds it improves cilium formation and reduces rhodopsin retention.

This paper develops a functional precision medicine approach using metabolic imaging to predict glioblastoma treatment response early in ex-vivo organoids, identifying responder and non-responder groups and a new molecular signature.