Cancer BiologybioRxivPreprint
TGFBR2-High mesenchymal glioma stem cells phenocopy regulatory T cells to suppress CD4+ and CD8+ T cell function
Amanda Johnson, Harmon Singh Khela, Jack Korleski…·John Laterra
The paper identifies TGFBR2-high mesenchymal glioma stem cells that mimic regulatory T cells and suppress T cell function, showing TGFBR2 inhibition can reverse this effect.