NeuroscienceAgingPeer-reviewed
PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway
Mihyang Do, Jeongmin Park, Yubing Chen…·Hun‐Taeg Chung
This study shows that SB202190 activates PERK, which enhances TFEB activity and the autophagy-lysosomal pathway, reducing amyloidogenesis in neurodegenerative diseases.
10 citations