Cancer BiologybioRxivPreprint
L1CAM-CAR T cells with enhanced potency overcome low-density antigen expression in rhabdomyosarcoma
Caroline Piccand, Corentin Gauthier, Sara G. Danielli…·Michele Bernasconi
This study develops L1CAM-CAR T cells that effectively target rhabdomyosarcoma despite low antigen density, showing improved efficacy and safety compared to existing CARs.
DOI 10.64898/2026.02.27.707949