Sigma factors as potential targets to enhance recombinant protein expression
Laura Pohlen, Emily García, Luz María Martínez, Noemí Flores, Jochen Büchs, Guillermo Gosset, Alvaro R. Lara
This study evaluates sigma factor deletions in E. coli to improve recombinant protein production, finding that rpoD and rpoS mutants show enhanced expression in specific media and conditions.
Biotechnology and Bioengineering · Feb 24, 2025Peer-reviewedMicrobiology