Model-Driven Hybrid AI Framework for End-to-End Autonomous Decision-Making in Drug Development
Hyunjung Lee, Hongmei Kang, Woojin Jung, Hyojin Cho, Sungwoo Goo, Hwi-yeol Yun, Min‐Gul Kim, Jung‐woo Chae, Sang-Min Park, Soyoung Lee, Jae Hyun Kim, Sangkeun Jung
This paper introduces a hybrid AI framework for drug development that links clinical questions to pharmacokinetic simulations and decision support using PICO specifications and machine learning.
bioRxiv · Feb 6, 2026 · PreprintPharmacology & Toxicology