Author

Laurence Armand-Lefèvre

InsermORCID 0000-0002-2013-3252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:E. coli· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Érick DenamuriD· 2 shared Marie PetitjeaniD· 2 shared Signara GueyeiD· 2 shared Thibaut Morel‐JourneliD· 2 shared Valentine BertiiD· 2 shared André BirgyiD· 1 shared Christelle LougbegnoniD· 1 shared Emilie MallecotiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Érick DenamurORCID

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2 papers

Recent·Most cited

Chromosomal integration of blaCTX-M redefines the evolutionary trajectory of antibiotic resistance in E. coli through lineage-structured expansion

Maxime Danjean, Thibaut Morel‐Journel, Valentine Berti, Yasmine Benhadid-Brahmi, Signara Gueye, Christelle Lougbegnon, Hervé Jacquier, Érick Denamur, Stephane Bonacorsi, Patricia Siguier, François Cornet, Manuel Campos, Marie Petitjean, André Birgy, Laurence Armand-Lefèvre

The paper identifies chromosomal integration of blaCTX-M in E. coli, showing lineage-specific prevalence and suggesting it contributes to the spread of antibiotic resistance.

bioRxiv · Oct 8, 2026 · PreprintMicrobiology

Influence of iron uptake systems on cefiderocol activity in Escherichia coli: at the crossroads of antibiotic resistance and virulence

Emilie Mallecot, Valentine Berti, Marie Petitjean, Julie Meyer, Signara Gueye, Thibaut Morel‐Journel, Sarah Timsit, Olivier Clermont, Laurent Poirel, Érick Denamur, Guilhem Royer, Laurence Armand-Lefèvre

This study examines how iron uptake systems affect cefiderocol activity in E. coli, showing that the fec operon increases resistance and is linked to virulence.

Antimicrobial Agents and Chemotherapy · Jul 10, 2026Peer-reviewedMicrobiology