Author

Thibaut Morel‐Journel

InsermORCID 0000-0002-9124-2894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Organism:E. coli· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Érick DenamuriD· 3 shared André BirgyiD· 2 shared Laurence Armand-LefèvreiD· 2 shared Marie PetitjeaniD· 2 shared Signara GueyeiD· 2 shared Valentine BertiiD· 2 shared A. WerneriD· 1 shared Assiya El Mniai· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

Érick DenamurORCID

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Author profile →

5 papers

Recent·Most cited

Chromosomal integration of blaCTX-M redefines the evolutionary trajectory of antibiotic resistance in E. coli through lineage-structured expansion

Maxime Danjean, Thibaut Morel‐Journel, Valentine Berti, Yasmine Benhadid-Brahmi, Signara Gueye, Christelle Lougbegnon, Hervé Jacquier, Érick Denamur, Stephane Bonacorsi, Patricia Siguier, François Cornet, Manuel Campos, Marie Petitjean, André Birgy, Laurence Armand-Lefèvre

The paper identifies chromosomal integration of blaCTX-M in E. coli, showing lineage-specific prevalence and suggesting it contributes to the spread of antibiotic resistance.

bioRxiv · Oct 8, 2026 · PreprintMicrobiology

Influence of iron uptake systems on cefiderocol activity in Escherichia coli: at the crossroads of antibiotic resistance and virulence

Emilie Mallecot, Valentine Berti, Marie Petitjean, Julie Meyer, Signara Gueye, Thibaut Morel‐Journel, Sarah Timsit, Olivier Clermont, Laurent Poirel, Érick Denamur, Guilhem Royer, Laurence Armand-Lefèvre

This study examines how iron uptake systems affect cefiderocol activity in E. coli, showing that the fec operon increases resistance and is linked to virulence.

Antimicrobial Agents and Chemotherapy · Jul 10, 2026Peer-reviewedMicrobiology

Quantifying the mechanisms of vaccine-induced serotype replacement in Streptococcus pneumoniae using genome-informed modelling

Zein Assad, Kévin La, Corinne Lévy, Robert Cohen, Assiya El Mniai, Inès Fafi, Zaba Valtuille, Stéphane Béchet, François Corrard, A. Werner, Christophe Rodriguez, Mélissa N’Debi, Stephanie W. Lo, Lindsay Osei, Manon Jaboyedoff, , Naïm Ouldali

The paper quantifies how serotype replacement in Streptococcus pneumoniae is driven by shifts in serotypes within persistent lineages rather than lineage replacement, using genome-informed modeling and longitudinal data.

bioRxiv · Jul 1, 2026 · PreprintMicrobiology

Quantifying the effects of antibiotic resistance and within-host competition on strain fitness in Streptococcus pneumoniae

Aswin Krishna, Gerry Q. Tonkin‐Hill, Thibaut Morel‐Journel, Stephen D. Bentley, Paul Turner, François Blanquart, Sonja Lehtinen

This study quantifies how antibiotic resistance and within-host competition affect pneumococcal strain fitness using longitudinal carriage data.

bioRxiv · Mar 9, 2025 · PreprintEcology

IncC plasmid genome rearrangements influence the vertical and horizontal transmission tradeoff in Escherichia coli

Margaux Allain, Thibaut Morel‐Journel, Bénédicte Condamine, Benoist Gibeaux, Benoît Gachet, Rémi Gschwind, Érick Denamur, Luce Landraud

This study shows that IncC plasmid genome rearrangements enhance horizontal transmission while maintaining bacterial fitness, suggesting a strategy for plasmid dissemination.

Antimicrobial Agents and Chemotherapy · Aug 28, 2024Peer-reviewedMicrobiology