Author

Jon‐Fredrik Nielsen

University of MichiganORCID 0000-0002-2058-3579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Assay:imaging· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Amaya MurguiaiD· 2 shared Andrea M. JacobsoniD· 2 shared Jeffrey A. FessleriD· 2 shared Navid Seraji‐BozorgzadiD· 2 shared Scott D. SwansoniD· 2 shared Berkin BilgiçiD· 1 shared Borjan A. GagoskiiD· 1 shared Carl‐Fredrik WestiniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

Amaya MurguiaORCID

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3 papers

Recent·Most cited

Phantom- and simulation-based validation of combined diffusion relaxometry in ex vivo ADRD white matter

Andrea M. Jacobson, Amaya Murguia, Scott D. Swanson, Jon‐Fredrik Nielsen, Jeffrey A. Fessler, Navid Seraji‐Bozorgzad

This paper validates combined T2-Diffusion MRI in ex vivo ADRD white matter using phantoms and simulations, showing accurate resolution of myelin and axonal water signatures.

bioRxiv · Apr 30, 2026 · PreprintBioengineering

Impact of Tissue Sample Preparation Methods on Myelin-Sensitive Quantitative MR Imaging

Amaya Murguia, Scott D. Swanson, Ulrich M. Scheven, Andrea M. Jacobson, Jon‐Fredrik Nielsen, Jeffrey A. Fessler, Navid Seraji‐Bozorgzad

The paper compares myelin-sensitive MRI parameters in fresh, thawed, and fixed sheep brain tissue, finding that freezing preserves tissue integrity but alters MRI values compared to fresh tissue.

Magnetic Resonance in Medicine · Jul 25, 2025Peer-reviewedBioengineering

Time-division multiplexing (TDM) sequence removes bias in T2 estimation and relaxation-diffusion measurements

Qiang Liu, Borjan A. Gagoski, Imam Ahmed Shaik, Carl‐Fredrik Westin, Elisabeth A. Wilde, Walter Schneider, Berkin Bilgiç, William A. Grissom, Jon‐Fredrik Nielsen, Maxim Zaitsev, Yogesh Rathi A, Lipeng Ning

This study compares multi-echo and time-division multiplexing sequences for relaxation-diffusion MRI, finding TDM provides more accurate T2 estimates and microstructure measures with faster acquisition.

Magnetic Resonance in Medicine · Aug 13, 2024Peer-reviewedNeuroscience