Molecular BiologyGenome biologyPeer-reviewed
A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 nucleases in rice
Xu Dong Tang, Guanqing Liu, Jianping Zhou…·Yong Zhang
This study uses whole-genome sequencing to analyze off-target mutations in Cas9 and Cpf1-edited rice, finding most mutations arise from tissue culture rather than nuclease activity.
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