Dengwei Zhang

This study identifies health-associated gut bacteriocins that target TLR4 to suppress intestinal inflammation in murine models.

The paper introduces IIBacFinder to identify unmodified class II bacteriocins in the human gut microbiome, showing their widespread distribution and biosynthetic potential.

This paper identifies twenty-four new archaeal lanthipeptides with unique chemical features and ecological functions, expanding the known chemical diversity of archaeal secondary metabolites.

This study identifies diverse ribosomally synthesized peptides in the human microbiome and shows some inhibit pathogens and reduce inflammation.

CRISPR-Detector detects, visualizes, and annotates genome-wide mutations from CRISPR/Cas gene editing events with improved speed, scalability, and accuracy.

The paper identifies diverse antagonistic bacteriocins from lactic acid bacteria in the human microbiome using metagenomic and metatranscriptomic analysis.

BDdb is a database integrating multi-omics data, cfDNA data, and biomarkers for birth defects, enabling data exploration and analysis for research and clinical applications.

The paper compares human and mouse neocortical development using scRNA-seq, finding differences in excitatory neuron trajectories and gene expression but conservation in glial and inhibitory neuron development.

This study uses whole-genome sequencing to analyze off-target mutations in Cas9 and Cpf1-edited rice, finding most mutations arise from tissue culture rather than nuclease activity.