BiochemistryAngewandte Chemie International EditionPeer-reviewed
Protein-Driven Copper Redox Regulation: Uncovering the Role of Disulphide Bonds and Allosteric Modulation
Rebecca Sternke‐Hoffmann, Chang Liu, Xue Bing Wang…·Jinghui Luo
This study identifies a redox mechanism in human serum albumin (HSA) that reduces Cu(II) to Cu(I) via disulphide bonds and conformational changes, revealing a new role for protein-mediated copper regulation.
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