Xue Bing Wang

This study identifies a redox mechanism in human serum albumin (HSA) that reduces Cu(II) to Cu(I) via disulphide bonds and conformational changes, revealing a new role for protein-mediated copper regulation.

This study uses multi-omics data to analyze immune and metabolic changes in mountain climbers during acclimatization and extreme altitude exposure.

The paper performs large-scale proteomic analysis of Alzheimer's disease brain regions across different racial and ethnic groups, identifying AD-related protein changes and APOE4 concordance with genotype.

The paper identifies lysine monomethylation on Tau by SETD7 in human brain tissue and shows its association with nuclear Tau in a mouse model of tauopathy.

Coexpression meta-analysis of 2114 human brain RNA-seq samples across the AMP-AD consortium identifies five consensus Alzheimer's disease transcriptional clusters, including two sex-heterogeneous clusters and a previously unreported proteostasis cluster.