Rapid turnover of corticosterone in humans: the role of a second glucocorticoid hormone
Mark Nixon, Scott D. Mackenzie, Kerri Devine, Catriona J. Kyle, Rita Upreti, Natalie Z. M. Homer, Rebecca M. Reynolds, Ruth Andrew, Brian Robert Walker, Roland H. Stimson
This study investigates corticosterone metabolism and dynamics in humans, finding it has faster turnover, greater metabolism, and a stronger ACTH response compared to cortisol.
bioRxiv · Apr 29, 2026 · PreprintPharmacology & Toxicology