Author
The Queen's Medical Research InstituteORCID 0000-0002-2416-1648Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Mark Nixon, Scott D. Mackenzie, Kerri Devine…·Roland H. Stimson
This study investigates corticosterone metabolism and dynamics in humans, finding it has faster turnover, greater metabolism, and a stronger ACTH response compared to cortisol.
Alexandra J. Malbon, Alicja Czopek, Andrew Michael Beekman…·Ruth A. Morgan
This study identifies CBR1 as a regulator of blood pressure in Down Syndrome, showing that its inhibition can increase blood pressure in a DS mouse model.
Sean Bankier, Lingfei Wang, Andrew A. Crawford…·Tom Michoel
The paper identifies genetic variants associated with plasma cortisol and cardiovascular disease, revealing gene networks in liver and adipose tissues regulated by corticosteroid binding globulin and the glucocorticoid receptor.
Sam O Kleeman, Tuba Mansoor Thakir, Breanna R. Demestichas…·et al
This study identifies Cystatin C as a glucocorticoid-responsive factor that recruits Trem2+ macrophages and predicts immunotherapy failure in cancer.
Fiona A. Hagenbeek, Jenny van Dongen, René Pool…·Dorret Irene Boomsma
This study examines heritability of urinary metabolites in children, finding substantial genetic contributions across amines, organic acids, and steroids.
Daniel S. Tylee, Jiayin Sun, Jonathan L. Hess…·Stephen J. Glatt
The paper investigates genetic correlations between psychiatric and immune-related phenotypes using GWAS summary data, finding significant shared genetic variants.