Author

Francesca D. Spagnuolo

Trinity College DublinORCID 0000-0002-2093-8923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:organoid / primary culture· 2 Research Focus:clustering· 1

Frequent Co-Authors

Daniel John KellyiD· 3 shared Gabriela S. KronembergeriD· 3 shared Aliaa KaramiD· 1 shared Kaoutar ChattahyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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3 shared papersBioengineering

Daniel John KellyORCID

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3 papers

Recent·Most cited

Spatiotemporal bioprinting of microtissues and growth factors within a support bath to engineer anisotropic, zonally defined meniscal grafts

Francesca D. Spagnuolo, Gabriela S. Kronemberger, Daniel John Kelly

This paper develops a bioprinting method to create zonally defined meniscal grafts using growth factors and MSC-derived microtissues, resulting in scaffold-free tissues with region-specific ECM composition.

bioRxiv · Jul 23, 2026 · PreprintBioengineering

A 4D Bioprinting Platform to Engineer Anisotropic Musculoskeletal Tissues by Spatially Patterning Microtissues into Temporally Adapting Support Baths

Francesca D. Spagnuolo, Gabriela S. Kronemberger, D. A. Kelly

This paper introduces a 4D bioprinting platform that engineers anisotropic musculoskeletal tissues by controlling support bath stiffness to direct cell behavior and matrix organization.

Advanced Science · Feb 6, 2026Peer-reviewedBioengineering

Bioassembly of region-specific fibrocartilage microtissues to engineer zonally defined meniscal grafts

Gabriela S. Kronemberger, Kaoutar Chattahy, Francesca D. Spagnuolo, Aliaa Karam, Daniel John Kelly

This study biofabricates zonally defined meniscal grafts using inner and outer meniscus progenitor cell microtissues, showing phenotypic similarity to native meniscus.

Advanced Healthcare Materials · Aug 21, 2025Peer-reviewedBioengineering