Leena Yoon

This study shows macroH2A limits EBV replication by restricting H2A.Z and EBNA1 binding at oriP, reducing DNA damage signaling and episomal replication.

ERVmancer is a phylogeny-informed method that resolves read-mapping ambiguity for HERVs, outperforming existing approaches and revealing new biology in breast cancer.

This study identifies CDC7 and POU2F1 as direct targets of EBNA1 in EBV+ epithelial cancers using VK1727 inhibition, revealing new therapeutic strategies.

This study uses an ex vivo PBMC model to show that monocyte and Treg dynamics determine EBV infection outcomes, with LIPA and Tregs playing key roles in antiviral responses and LCL outgrowth.

The paper shows LANA binding at KSHV TRs causes R-loops and histone modifications linked to episome maintenance.

This study shows H2A.Z.1 works with EBNA1 to maintain EBV latency by regulating chromatin structure and gene expression.