Author

Francisco J. R. Ruiz

University of CambridgeORCID 0000-0002-2200-901XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Anna LasorellaiD· 1 shared Antonio IavaroneiD· 1 shared David M. BleiiD· 1 shared Erin C. BushiD· 1 shared Hanna Mendes Levitin· 1 shared Jeffrey N. BruceiD· 1 shared Jinzhou YuaniD· 1 shared Peter A. SimsiD· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Anna LasorellaORCID

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1 paper

Recent·Most cited

Systems BiologyMolecular Systems BiologyPeer-reviewedFeb 1, 2019

De novo Gene Signature Identification from Single-Cell RNA-Seq with Hierarchical Poisson Factorization

Hanna Mendes Levitin, Jinzhou Yuan, Yim Ling Cheng…·Peter A. Sims

This paper introduces scHPF, a Bayesian method for discovering gene signatures from scRNA-seq without prior normalization, and finds spatially biased expression patterns in glioma regions linked to poor survival.

107 citationstop 4%

humanscRNA-seq

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