Erin C. Bush

This study identifies a dietary lipid axis driven by linoleic acid and FADS2 that suppresses antitumor immunity in liver cancer, offering a therapeutic target for immunotherapy resistance.

The paper identifies treatment-resistant Cancer Stem-Like Cells in breast cancer using single-cell RNA sequencing and validates a drug combination to target them effectively.

This paper introduces scHPF, a Bayesian method for discovering gene signatures from scRNA-seq without prior normalization, and finds spatially biased expression patterns in glioma regions linked to poor survival.