Molecular BiologybioRxivPreprint
Preeclampsia in mice carrying fetuses with APOL1 risk variants
Teruhiko Yoshida, Khun Zaw Latt, Shashi Shrivastav…·Jeffrey B. Kopp
This study uses mouse models to show that fetal APOL1-G1 variants cause preeclampsia by inducing pro-inflammatory responses in placental and maternal monocyte cells.