Sandra E. Reznik

A two-dose DMA regimen on gestational day 15 prevented LPS-induced preterm birth in CD-1 mice, reversed cytokine surges within days, and spared term parturition.

This study compares vaginal and intraperitoneal dimethylacetamide formulations in a mouse model of preterm birth, finding similar efficacy but lower systemic concentrations with vaginal delivery.

This study uses mouse models to show that fetal APOL1-G1 variants cause preeclampsia by inducing pro-inflammatory responses in placental and maternal monocyte cells.