Synthetic BiologybioRxivPreprint
Machine learning-guided directed evolution for the development of small-molecule antibiotics originating from antimicrobial peptides
Heqian Zhang, Yihan Wang, Pengtao Huang…·Zhiwei Qin
This study uses machine learning-guided directed evolution to develop a peptide antibiotic from antimicrobial peptides, showing improved antimicrobial activity and therapeutic potential.