Author

Karthik Ramaswamy

John Sealy HospitalORCID 0000-0002-2245-7541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Balaji KrishnaniD· 2 shared Chandramouli Natarajan· 2 shared Sanjana MohantyiD· 2 shared Agenor LimóniD· 1 shared Enoch Wong· 1 shared Jose L Lopez· 1 shared Joshua Currie· 1 shared Klarissa H GarzaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Balaji KrishnanORCID

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2 papers

Recent·Most cited

Repeated VU0155069 Treatment Is Associated with Region- and Pathological Stage-Specific Dendritic Spine Remodeling in Female 3xTg-AD Mice

Sanjana Mohanty, Sarah Bosworth, Karthik Ramaswamy, Chandramouli Natarajan, Balaji Krishnan

This study shows that repeated VU0155069 treatment causes region- and stage-specific dendritic spine remodeling in female 3xTg-AD mice, affecting multiple brain circuits.

bioRxiv · Oct 27, 2026 · PreprintNeuroscience

PLD1-Dependent Regulation of Synaptic Integrity: Implications for Cognitive Resilience and Alzheimer's Disease Pathogenesis

Sravan Gopalkrishnashetty Sreenivasmurthy, Shaneilahi M. Budhwani, Sanjana Mohanty, Marlene E Villarreal, Poonam Shah, Shyny K John, Chandramouli Natarajan, Karthik Ramaswamy, Kyle Sheth, Enoch Wong, Phu Cuong Phan, Jose L Lopez, Satkarjeet Kaur Gill, Joshua Currie, Klarissa H Garza, , Balaji Krishnan

This study shows that modulating PLD1 affects synaptic integrity and cognition in aging and Alzheimer's disease models, with PLD1 attenuation improving synaptic function and memory in AD mice.

bioRxiv · Dec 11, 2025 · PreprintNeuroscience