Author

Fiona D. Ehrich

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-2245-9352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:spatial transcriptomics· 2 Approach:Bayesian inference· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Caroline E. KostrzewaiD· 2 shared James William SmithyiD· 2 shared Katherine S. PanageasiD· 2 shared Margaret K. CallahaniD· 2 shared Michael Andrew PostowiD· 2 shared Mohammad YosofvandiD· 2 shared Ronglai SheniD· 2 shared Xiyu PengiD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Caroline E. KostrzewaORCID

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2 papers

Recent·Most cited

Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis

Xiyu Peng, James William Smithy, Mohammad Yosofvand, Caroline E. Kostrzewa, MaryLena Bleile, Fiona D. Ehrich, Jasme Lee, Michael Andrew Postow, Margaret K. Callahan, Katherine S. Panageas, Ronglai Shen

The paper introduces SpatialTopic, a Bayesian topic model for multiplexed imaging analysis that identifies spatial features and tracks their dynamics across disease progression.

bioRxiv · Oct 8, 2024 · PreprintBioinformatics

Spatial Immunophenotyping from Whole-Slide Multiplexed Tissue Imaging Using Convolutional Neural Networks

Mohammad Yosofvand, Sharon N. Edmiston, James William Smithy, Xiyu Peng, Caroline E. Kostrzewa, Bridget Lin, Fiona D. Ehrich, Allison Reiner, Jayson Miedema, Andrea Primiani Moy, Irene Orlow, Michael Andrew Postow, Katherine S. Panageas, Venkatraman Seshan, Margaret K. Callahan, , Ronglai Shen

CellGate automates spatial immunophenotyping of multiplexed tissue images with high accuracy, enabling scalable analysis of tumor-immune microenvironments.

bioRxiv · Aug 16, 2024 · PreprintBioinformatics