Winny Sun

Alterations to the yeast chromatin landscape during hypoxia

This study investigates chromatin changes in yeast under hypoxia, showing reduced H3K9ac and increased H3K4me3 levels, with implications for gene regulation and survival.

Set1 regulates telomere function via H3K4 methylation-dependent and independent pathways and calibrates the abundance of telomere maintenance factors

This study investigates Set1's role in telomere maintenance through catalytic and non-catalytic functions in yeast, revealing H3K4 methylation-dependent and independent mechanisms.

Set4 coordinates the activity of histone deacetylases and regulates stress-responsive gene expression within subtelomeric regions in yeast

This study identifies Set4 as a regulator of subtelomeric gene expression and chromatin repression in yeast, showing its role in stress response and cell fitness under hypoxia.