Author

Jiayi He

Center for Life SciencesORCID 0000-0002-2267-3666Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

JIayi He1 paper · Whitehead Institute for Biomedical Research

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Assay:CUT&Tag· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Lingzhao FangiD· 2 shared Pengju ZhaoiD· 2 shared Chen PengiD· 1 shared Chunhuan ReniD· 1 shared Dailu GuaniD· 1 shared David Evan MacHughiD· 1 shared Emily L. ClarkiD· 1 shared Fei Liu· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Lingzhao FangORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 26, 2026

✦ In-depth digest

A multi-tissue epigenomic atlas links the sheep non-coding genome to domestication and complex traits

Zhu Meng, Shiwen Zhang, Ziyang Zhuang…·Zhangyuan Pan

SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.

DOI 10.64898/2026.08.22.746371

multiple specieshuman

BioinformaticsbioRxivPreprintMar 31, 2026

LATTE for locus-specific quantification of transposable element expression across species

JIayi He, Chen Peng, Yuelang Zhang…·Pengju Zhao

LATTE quantifies TE expression across species and identifies TE-eQTLs, revealing distinct regulatory mechanisms and additional associations with complex traits.

DOI 10.64898/2026.03.28.714964

NeuroscienceBiology of the CellPeer-reviewedNov 1, 2025

Fasting Rescues Locomotion in Neuromodulation-Deficient C. elegans via Octopamine-Gαq Signaling

Jiayi He, Zi Wang, Guangshuo Ou, Wěi Li

The paper shows fasting improves locomotion in C. elegans lacking UNC-31/CAPS by activating octopamine-Gαq signaling through upregulation of egl-30.

1 citation

C. elegansstatistical model