Neurologically altered brain activity may not look like aged brain activity: Implications for brain-age modeling and biomarker strategies
Lukas A. W. Gemein, Sinead Gaubert, Claire Paquet, Joseph Paillard, Sebastian C. Holst, Thomas Tveitstøl, Ira Haraldsen, David J. Hawellek, Joerg F. Hipp, Denis Alexander Engemann
This study shows that brain-age gaps from EEG spectral power in neurological populations do not reflect accelerated aging, challenging the use of EEG as a biomarker for neurodegeneration.
bioRxiv · Apr 15, 2025 · PreprintNeuroscience