Sebastian C. Holst

This paper models the effect of V1a receptor antagonism on circadian rhythms in mice, showing it accelerates resynchronization and suggests therapeutic potential for circadian disorders.

This study shows that brain-age gaps from EEG spectral power in neurological populations do not reflect accelerated aging, challenging the use of EEG as a biomarker for neurodegeneration.

This study predicts age from at-home EEG data during sleep and meditation, achieving R2 scores of 0.3-0.5, comparable to lab-grade EEG benchmarks.

This study quantifies how sleep affects physiological brain pulsations and shows that spectral entropy of these pulsations can distinguish sleep from awake states.

This study links an AQP4 haplotype to variations in NREM slow wave energy and cognitive performance during wakefulness in humans.

The paper examines changes in cerebral and peripheral markers of glutamatergic signaling across the human sleep-wake cycle and finds that sleep loss increases glutamate and mGluR5 availability, which normalize with recovery sleep.