Author

Nicholaus L. DeCuzzi

University of California, DavisORCID 0000-0002-2275-4933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

John G. AlbeckiD· 3 shared Michael PargettiD· 2 shared Brayant Rodriguez· 1 shared Christina C. AbbateiD· 1 shared Christopher S. FraseriD· 1 shared Elijah Kofke· 1 shared Florene XuiD· 1 shared Jason J. HuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

John G. AlbeckORCID

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3 papers

Recent·Most cited

The eIF4B RNA recognition motif promotes higher-order organization of the translation initiation machinery during stress granule assembly.

Jessica Bolivar, Nicholaus L. DeCuzzi, Elijah Kofke, Masaaki Sokabe, Katherine M Beglinger, John G. Albeck, Christopher S. Fraser

This study shows that the eIF4B RRM regulates stress granule assembly and translational repression during oxidative stress.

bioRxiv · Aug 27, 2026 · PreprintCell Biology

A Far-Red FRET biosensor for AMPK enables multiplexed imaging of single-cell bioenergetic homeostasis

Nicholaus L. DeCuzzi, Marion Hardy, Markhus Cabel, Jason Y Hu, Christina C. Abbate, Michael Pargett, John G. Albeck

The paper introduces a far-red FRET biosensor for AMPK activity, enabling multiplexed imaging of single-cell bioenergetic homeostasis and reveals kinetic coupling between AMPK and ATP/ADP ratio.

bioRxiv · May 18, 2026 · PreprintSystems Biology

Two Novel Red-FRET ERK Biosensors in the 670-720nm Range.

Nicholaus L. DeCuzzi, Jason J. Hu, Florene Xu, Brayant Rodriguez, Michael Pargett, John G. Albeck

This paper develops two red-FRET ERK biosensors, REKAR67 and REKAR76, which operate in the 670-720 nm range and are spectrally compatible with existing biosensors for single-cell ERK activity measurement.

Journal of Biological Engineering · Nov 13, 2025Peer-reviewedCell Biology