Author

Guo‐Cheng Yuan

Harvard UniversityORCID 0000-0002-2283-4714Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 14 Genomics· 6 Molecular Biology· 4 Systems Biology· 3 Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 22 Research Focus:gene regulatory network inference· 13 Organism:mouse· 13 Assay:spatial transcriptomics· 11 Approach:experimental assay· 10 Assay:ChIP-seq· 9 Research Focus:differential expression· 9 Assay:scRNA-seq· 9

Frequent Co-Authors

Stuart H. OrkiniD· 7 shared Long CaiiD· 6 shared Qian ZhuiD· 6 shared Shengbao SuoiD· 5 shared Shiwei ZhengiD· 5 shared Luca PinelloiD· 4 shared Panos RoussosiD· 4 shared Jina YuniD· 3 shared

Activity by Year

2017-2026 · peak 7/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

7 shared papersMolecular Biology

Stuart H. OrkinORCID

Mutual co-authors in cluster

Author profile →

33 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedFeb 27, 2018

Dissecting super-enhancer hierarchy based on chromatin interactions

Jialiang Huang, Kailong Li, Wenqing Cai…·Guo‐Cheng Yuan

The paper identifies hub enhancers within super-enhancers using Hi-C and ChIP-seq data, showing their role in gene activation and chromatin structure.

241 citationstop 1%

Hi-CChIP-seq

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedJan 16, 2018

Haystack: systematic analysis of the variation of epigenetic states and cell-type specific regulatory elements

Luca Pinello, Rick Farouni, Guo‐Cheng Yuan

Haystack identifies epigenetic variability hotspots and cell-type specific regulatory elements across multiple cell types using a computational pipeline.

19 citations

humanChIP-seq

𝕏 PostBluesky

GenomicsGenome biologyPeer-reviewedMay 8, 2017

Challenges And Emerging Directions In Single-Cell Analysis

Guo‐Cheng Yuan, Long Cai, Michael B. Elowitz…·Itay Tirosh

This paper discusses challenges and future directions in single-cell analysis, highlighting advances in technologies and computational methods for studying cellular heterogeneity.

341 citationstop 4%

scRNA-seqstatistical model

𝕏 PostBluesky