Jingyi Wang

AbNovoBench: a resource and benchmarking platform for monoclonal antibody de novo sequencing

AbNovoBench benchmarks de novo sequencing algorithms for monoclonal antibodies using a large dataset and provides an online platform for antibody sequencing workflows.

Simplified and Rapid Workflow Enhances Throughput of De Novo Sequencing of COVID-19 Neutralizing Antibodies

This paper develops a rapid de novo sequencing workflow for COVID-19 neutralizing antibodies, achieving high accuracy in mixed antibody mixtures.

Comprehensive assembly of monoclonal and mixed antibody sequences

This paper introduces Fusion, a de novo assembler for antibody sequences, demonstrating high accuracy in reconstructing monoclonal and mixed antibody sequences from mass spectrometry data.

Protecting synapses from amyloid β-associated degeneration by manipulations of Wnt/planar cell polarity signaling

The paper investigates how Aβ oligomers disrupt Wnt/PCP signaling by interacting with Celsr3 and Vangl2, leading to synapse loss in Alzheimer's disease, and suggests potential therapeutic strategies.