MicrobiologymSystemsPeer-reviewed
Bridging in vitro and in vivo insights: A PKPD model for effective phage therapy against multidrug-resistant Pseudomonas aeruginosa
Jun Seok Cha, Kyungnam Kim, Hwa Jeong You…·Dongwoo Chae
This study develops a PKPD model integrating in vitro and in vivo data to optimize phage therapy against multidrug-resistant Pseudomonas aeruginosa, showing that phage combinations delay resistance but may lead to immune clearance of resistant mutants.
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