Diego Díez

DeepSpaceDB 2.0 expands its database to include 1,539 public Xenium datasets, offering improved tools for interactive exploration and analysis of spatial transcriptomics data.

DeepSpaceDB provides an interactive spatial transcriptomics database with advanced analysis tools for comparing gene expression across tissue regions and samples.

The paper shows that ZAP-70 mutations in mice lead to a shift in T cell repertoires, with pathogenic Th17 cells resembling Tregs and contributing to autoimmune arthritis.

The paper updates singleCellHaystack to predict differentially active features across single-cell, spatial, and bulk genomics data with improved performance and scalability.

Canek integrates single-cell transcriptome replicates by removing batch effects with minimal bias, using mutual nearest neighbor and fuzzy logic.

singleCellHaystack identifies differentially expressed genes in single-cell data without requiring clustering, using Kullback-Leibler Divergence to detect non-random gene expression patterns in 2D plots.