Jennifer L. Wilson

A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling

This study develops a computational workflow to assess drug effects on NFκB signaling dynamics, finding that temporal coding capacity is robust to pharmacological perturbations.

Controlling astrocyte-mediated synaptic pruning signals for schizophrenia drug repurposing with Deep Graph Networks

This paper uses Deep Graph Networks to predict compound effects on phagocytosis and identifies 64 potential schizophrenia treatments from an existing drug library.

From random to predictive: a context-specific interaction framework improves selection of drug protein-protein interactions for unknown drug pathways

The paper introduces a context-specific interaction framework to improve prediction of drug protein-protein interactions for unknown drug pathways, achieving higher accuracy than random methods.